SedLine® Brain Function Monitoring

SedLine® Brain Function Monitoring

SedLine® Brain Function Monitoring

 

Masimo is passionate about making innovative technologies that give clinicians the tools they need to do what is best for patient care. That's why it is gratifying to see so many clinicians and clinical researchers take the time to evaluate our products and technologies.

Click on the links below to read featured studies for Masimo’s technologies, or in the sections below for access by subject area to all studies.

Clinical Evidence

EEG response of dexmedetomidine during drug induced sleep endoscopy

Han L, Drover DR, Chen MC, Saxena AR, Eagleman SL, Nekhendzy V, Pritchard A, Capasso R. Front Neurosci. 2023 Jul 14;17:1144141. doi: 10.3389/fnins.2023.1144141.

Evaluation of patient state index, bispectral index, and entropy during drug induced sleep endoscopy with dexmedetomidine

Han L, Drover DR, Chen MC, Saxena AR, Eagleman SL, Nekhendzy V, Capasso R. J Clin Monit Comput. 2022 Dec 22. doi: 10.1007/s10877-022-00952-9.

Usefulness of bispectral index and patient state index during sevoflurane anesthesia in children: A prospective observational study

Jang YE, Kim EH, Lee JH, Kim JT, Kim HS. Medicine (Baltimore). 2022 Jul 29;101(30):e29925. doi: 10.1097/MD.0000000000029925. 

Management Based on Multimodal Brain Monitoring May Improve Functional Connectivity and Post-operative Neurocognition in Elderly Patients Undergoing Spinal Surgery

Yang S, Xiao W, Wu H, Liu Y, Feng S, Lu J, Wang T. Front Aging Neurosci. 2021 Jul 15;13:705287.

Sevoflurane requirements during electroencephalogram (EEG)-guided vs standard anesthesia Care in Children: A randomized controlled trial

Long MHY, Lim EHL, Balanza GA, Allen JC Jr, Purdon PL, Bong CL. J Clin Anesth. 2022 Jun 27;81:110913. doi: 10.1016/j.jclinane.2022.110913.

Impact of Processed Electroencephalography in Cardiac Surgery: A Retrospective Analysis

Jarry S, Halley I, Calderone A, Momeni M, Deschamps A, Richebé P, Beaubien-Souligny W, Denault A, Couture EJ. J Cardiothorac Vasc Anesth. 2022. doi:10.1053/j.jvca.2022.03.030

Processed Multiparameter Electroencephalogram-Guided General Anesthesia Management Can Reduce Postoperative Delirium Following Carotid Endarterectomy: A Randomized Clinical Trial

Xu N, Li LX, Wang TL, Jiao LQ, Hua Y, Yao DX, Wu J, Ma YH, Tian T, Sun XL. Front Neurol. 2021 Jul 12;12:666814. doi: 10.3389/fneur.2021.666814

Prevalence of Isoelectric Electroencephalography Events in Infants and Young Children Undergoing General Anesthesia.

Yuan et al. Anesth Analg 2019. doi: 10.1213/ANE.0000000000004221

Intraoperative effect of dexmedetomidine infusion during living donor liver transplantation: A randomized control trial.

Sayed E, Yassen KA. Saudi J Anaesth. 2016 Jul-Sep;10(3):288-94.

Comparison between two versions of the Patient State Index during propofol and sevoflurane anesthesia, with or without remifentanil.

Kuizenga M.H., Colin P.J., Vereecke H.E.M., Struys M.M.R.F. Proceedings from Euroanaesthesia 2017, Geneva, Switzerland. Abstract #01AP07-4.

Titration of Delivery and Recovery from Propofol, Alfentanil, and Nitrous Oxide Anesthesia.

Drover D.R., Lemmens H.J., Pierce E.T., Plourde G., Loyd G., Ornstein E., Prichep L.S., Chabot R.J., Gugino L. Anesthesiology 2002; 97:82–9.

Effects of sevoflurane and propofol on frontal electroencephalogram power and coherence.

Akeju O, Westover MB, Pavone KJ, Sampson AL, Hartnack KE, Brown EN, Purdon PL. Anesthesiology. 2014 Nov;121(5):990-8. doi:10.1097/ALN.0000000000000436.

Prospective Comparison of Patient State Index (PSI) Between Propofol Sedation and Intravenous Conscious Sedation During Colonoscopy

Goudra B., Singh P., Samuel A., Cifuentes E. American Society of Anesthesiologists 2014; A3158.

Sedation Spectrum in Patients Undergoing Advanced Gastrointestinal (GI) Endoscopic Procedures With Propofol

Goudra B., Singh P., Augustus S. American Society of Anesthesiologists 2014; A1230.

Is The Patient State Analyzer With The Psarray2 A Cost-Effective Alternative To The Bispectral Index Monitor During The Perioperative Period?

White P.F., Tang J., Ma H., Wender R.H., Sloninsky A., Kariger R. Anesth Analg. 2004 Nov;99(5):1429-35.

A Comparison Of Patient State Index And Bispectral Index Values During The Perioperative Period.

Chen X., Tang J., White P.F., Wender R.H., Ma H., Sloninsky A., Kariger R. Anesth Analg. 2002 Dec;95(6):1669-74.

Advanced Monitoring Is Associated with Fewer Alarm Events During Planned Moderate Procedure-Related Sedation: A 2-Part Pilot Trial.

Applegate RL 2nd, Lenart J, Malkin M, Meineke MN, Qoshlli S, Neumann M, Jacobson JP, Kruger A, Ching J, Hassanian M, Um M. Anesth Analg. 2016 Feb 1.

EEG response of dexmedetomidine during drug induced sleep endoscopy

Han L, Drover DR, Chen MC, Saxena AR, Eagleman SL, Nekhendzy V, Pritchard A, Capasso R. Front Neurosci. 2023 Jul 14;17:1144141. doi: 10.3389/fnins.2023.1144141.

Association between the Depth of Sevoflurane or Propofol Anesthesia and the Incidence of Emergence Agitation in Children: A Single-Center Retrospective Study.

Kanaya A, Mihara T, Tanaka S, Mikami M, Wagatsuma T, Yamauchi M. Tohoku J Exp Med. 2023 May 26;260(2):93-98. doi: 10.1620/tjem.2023.J018. 

Characteristics of Electroencephalogram in the Prefrontal Cortex during Deep Brain Stimulation of Subthalamic Nucleus in Parkinson’s Disease under Propofol General Anesthesia

Ling Y, Liu L, Wang S, Guo Q, Xiao Q, Liu Y, Qu B, Wen Z, Li Y, Zhang C, Wu B. Brain Sciences. 2023 Jan;13(1):62.

Evaluation of patient state index, bispectral index, and entropy during drug induced sleep endoscopy with dexmedetomidine

Han L, Drover DR, Chen MC, Saxena AR, Eagleman SL, Nekhendzy V, Capasso R. J Clin Monit Comput. 2022 Dec 22. doi: 10.1007/s10877-022-00952-9.

Isoelectric Electroencephalography in Infants and Toddlers during Anesthesia for Surgery: An International Observational Study

Yuan I, Xu T, Skowno J, Zhang B, Davidson A, von Ungern-Sternberg BS, Sommerfield D, Zhang J, Song X, Zhang M, Zhao P, Liu H, Jiang Y, Zuo Y, de Graaff JC, Vutskits L, Olbrecht VA, Szmuk P, Kurth CD; BRAIN Collaborative Investigators. Anesthesiology. 2022 Aug 1;137(2):187-200. doi: 10.1097/ALN.0000000000004262. 

Usefulness of bispectral index and patient state index during sevoflurane anesthesia in children: A prospective observational study

Jang YE, Kim EH, Lee JH, Kim JT, Kim HS. Medicine (Baltimore). 2022 Jul 29;101(30):e29925. doi: 10.1097/MD.0000000000029925. 

Validation of the patient State Index for monitoring sedation state in critically ill patients: a prospective observational study

Idei M, Seino Y, Sato N, et al. J Clin Monit Comput. 2022 Jun 4. doi: 10.1007/s10877-022-00871-9.

Sevoflurane requirements during electroencephalogram (EEG)-guided vs standard anesthesia Care in Children: A randomized controlled trial

Long MHY, Lim EHL, Balanza GA, Allen JC Jr, Purdon PL, Bong CL. J Clin Anesth. 2022 Jun 27;81:110913. doi: 10.1016/j.jclinane.2022.110913.

Impact of Processed Electroencephalography in Cardiac Surgery: A Retrospective Analysis

Jarry S, Halley I, Calderone A, Momeni M, Deschamps A, Richebé P, Beaubien-Souligny W, Denault A, Couture EJ. J Cardiothorac Vasc Anesth. 2022. doi:10.1053/j.jvca.2022.03.030

Perioperative Electroencephalogram Spectral Dynamics Related to Postoperative Delirium in Older Patients

Koch S, Windmann V, Chakravarty S, Kruppa J, Yürek F, Brown EN, Winterer G, Spies C; BioCog Study Group. Anesth Analg. 2021 Dec 1;133(6):1598-1607. doi: 10.1213/ANE.0000000000005668

Processed Multiparameter Electroencephalogram-Guided General Anesthesia Management Can Reduce Postoperative Delirium Following Carotid Endarterectomy: A Randomized Clinical Trial

Xu N, Li LX, Wang TL, Jiao LQ, Hua Y, Yao DX, Wu J, Ma YH, Tian T, Sun XL. Front Neurol. 2021 Jul 12;12:666814. doi: 10.3389/fneur.2021.666814

Management Based on Multimodal Brain Monitoring May Improve Functional Connectivity and Post-operative Neurocognition in Elderly Patients Undergoing Spinal Surgery

Yang S, Xiao W, Wu H, Liu Y, Feng S, Lu J, Wang T. Front Aging Neurosci. 2021 Jul 15;13:705287.

Early neuro-prognostication with the Patient State Index and suppression ratio in post-cardiac arrest patients

Kim et al. J Crit Care. 2021;65:149-155.

Loss of spectral alpha power during spine surgery: what could be wrong?

Lobo FA, Vacas S, Naranjo M. J Clin Monit Comput. 2021;10.1007/s10877-021-00720-1.

Modelling the PSI response in general anesthesia

Pérez GA, Pérez JAM, Álvarez ST, Morales JAR, Fragoso AML. [published online ahead of print, 2020 Jul 20]. J Clin Monit Comput. 2020;10. doi:10.1007/s10877-020-00558-z

High Incidence of Burst Suppression during Propofol Sedation for Outpatient Colonoscopy: Lessons Learned from Neuromonitoring.

Bloom J, Wyler D, Torjman MC, et al. Anesthesiol Res Pract. 2020;2020:7246570. Published 2020 Jun 19.

Electroencephalogram Burst-suppression during Cardiopulmonary Bypass in Elderly Patients Mediates Postoperative Delirium.

Pedemonte JC et al. Anesthesiology. 2020 Apr 24. doi:10.1097/ALN.0000000000003328.

ADAPT-2: A Randomized Clinical Trial to Reduce Intraoperative EEG Suppression in Older Surgical Patients Undergoing Major Noncardiac Surgery

Tang, Christopher J. BS*; Jin, Zhongnan PhD†; Sands, Laura P. PhD†; Pleasants, Devon BS*; Tabatabai, Sanam BS*; Hong, Yili PhD†; Leung, Jacqueline M. MD, MPH
March 9, 2020 - Volume Publish Ahead of Print - Issue - doi: 10.1213/ANE.0000000000004713

Population Pharmacodynamics of Propofol and Sevoflurane in Healthy Volunteers Using a Clinical Score and the Patient State Index: A Crossover Study.

Merel H. Kuizenga, Pieter J. Colin, Koen M. E. M. Reyntjens, Daan J. Touw, Hasan Nalbat, Froukje H. Knotnerus, Hugo E. M. Vereecke, Michel M. R. F. Struys; Anesthesiology 2019;.doi: 10.1097/ALN.0000000000002966.

Prevalence of Isoelectric Electroencephalography Events in Infants and Young Children Undergoing General Anesthesia.

Yuan et al. Anesth Analg 2019. doi: 10.1213/ANE.0000000000004221

Patient management algorithm combining processed electroencephalographic monitoring with cerebral and somatic near-infrared spectroscopy: a case series.

Couture EJ, Deschamps A, Denault AY. Can J Anaesth. 2019 Feb 1. doi: 10.1007/s12630-019-01305-y.

Electroencephalogram dynamics during general anesthesia predict the later incidence and duration of burst-suppression during cardiopulmonary bypass.

Plummer GS, Ibala R, Hahm E, An J, Gitlin J, Deng H, Shelton KT, Solt K, Qu JZ, Akeju O.  Clin Neurophysiol. 2019 Jan;130(1):55-60.

Association of electroencephalogram trajectories during emergence from anaesthesia with delirium in the post-anaesthesia care unit: an early sign of postoperative complications.

Hesse S, Kreuzer M, Hight D, Kreuzer M, Hight D, Gaskell A, Devari P, Singh D, Taylor NB, Whalin MK, Lee S Sleight JW, Garcia PS.  British Journal of Anaesthesia, 2018, https://doi.org/10.1016/j.bja.2018.09.016.

Prospective Study of Propofol Sedation Practice for Outpatient Colonoscopy: Is It Sedation or General Anesthesia?

Tuan A. Trinh, M.D., Amy K. Mehta, M.D., Kristi M. Neitzel, M.D., Evan Fitchett, B.S., David A. Wyler, M.D., Michael E. Mahla, M.D., Marc C. Torjman, Ph.D., Victor M. Romo, M.D.
Proceedings from the Annual American Society of Anesthesiologists Meeting, San Francisco, October 2018.

Bispectral Index (BIS) and Patient State Index (PSI) During Desflurane Anesthesia

Mai Kato, M.D., Chiyoko Tanahira, M.D., Yoshihiro Ikuta, M.D., Michiko Sugita, M.D., Tatsuo Yamamoto, M.D.
Proceedings from the Annual American Society of Anesthesiologists Meeting, San Francisco, October 2018.

Perioperative Factors Associated with EEG Suppression in Older Surgical Patients

Cody Roberts, B.S., Laura P. Sands, Ph.D., Zhongnan Jin, B.S., Devon Pleasants, B.S., Christopher Tang, B.S., Jacqueline M. Leung, M.D.,M.P.H.
Proceedings from the Annual American Society of Anesthesiologists Meeting, San Francisco, October 2018.

Unusual elevation in Entropy but not in PSI during general anesthesia: a case report.

Kim YS, Chung D, Oh SK, Won YJ, Lee IO. BMC Anesthesiol. 2018 Feb 14;18(1):22.

The Technology of Processed Electroencephalogram Monitoring Devices for Assessment of Depth of Anesthesia.

Fahy BG, Chau DF. Anesth Analg. 2018 Jan;126(1):111-117. doi: 10.1213/ANE.0000000000002331. Review.

Patient State Index versus Bispectral Index in cirrhotic patients and non-cirrhotics undergoing hepatic resection: A controlled randomized study.

Yassen K, Elsheikh M, Helal S, Badawy E, Metwally A. Proceedings from Euroanaesthesia 2018, Copenhagen, Denmark.

Epileptiform discharge detection with the 4-channel frontal electroencephalography during post-resuscitation care.

You KM, Suh GJ, Kwon WY, Kim KS, Ko SB, Park MJ, Kim T, Ko JI. Resuscitation. 2017 Aug;117:8-13. doi: 10.1016/j.resuscitation.2017.05.016. Epub 2017 May 13. PubMed PMID: 28511986.

Burst-suppression ratio underestimates absolute duration of electroencephalogram suppression compared with visual analysis of intraoperative electroencephalogram.

Muhlhofer WG, Zak R, Kamal T, Rizvi B, Sands LP, Yuan M, Zhang X, Leung JM. Br J Anaesth. 2017 May 1;118(5):755-761. doi: 10.1093/bja/aex054. PubMed PMID: 28486575.

Intraoperative effect of dexmedetomidine infusion during living donor liver transplantation: A randomized control trial.

Sayed E, Yassen KA. Saudi J Anaesth. 2016 Jul-Sep;10(3):288-94.

Advanced Monitoring Is Associated with Fewer Alarm Events During Planned Moderate Procedure-Related Sedation: A 2-Part Pilot Trial.

Applegate RL 2nd, Lenart J, Malkin M, Meineke MN, Qoshlli S, Neumann M, Jacobson JP, Kruger A, Ching J, Hassanian M, Um M. Anesth Analg. 2016 Feb 1.

Propofol and non-propofol based sedation for outpatient colonoscopy-prospective comparison of depth of sedation using an EEG based SEDLine monitor.

Goudra B, Singh PM, Gouda G, Borle A, Carlin A, Yadwad A. J Clin Monit Comput. 2015 Sep 12. [Epub ahead of print] PubMed PMID: 26364193.

The Ageing Brain: Age-dependent changes in the electroencephalogram during propofol and sevoflurane general anaesthesia.

Purdon PL, Pavone KJ, Akeju O, Smith AC, Sampson AL, Lee J, Zhou DW, Solt K, Brown EN. Br J Anaesth. 2015 Jul;115 Suppl 1:i46-i57. doi: 10.1093/bja/aev213. PMID: 26174300 [PubMed - in process]

SEDLine Monitored Sedation and Recovery for Postoperative Ventilated Recipients of Living Donor Liver Transplantation: A Randomized Controlled Trial.

Sayed E and Refaat EK.  J Anesth Clin Res. 2015;5(6):1-6.

Effects of sevoflurane and propofol on frontal electroencephalogram power and coherence.

Akeju O, Westover MB, Pavone KJ, Sampson AL, Hartnack KE, Brown EN, Purdon PL. Anesthesiology. 2014 Nov;121(5):990-8. doi:10.1097/ALN.0000000000000436.

Prospective Comparison of Patient State Index (PSI) Between Propofol Sedation and Intravenous Conscious Sedation During Colonoscopy

Goudra B., Singh P., Samuel A., Cifuentes E. American Society of Anesthesiologists 2014; A3158.

Sedation Spectrum in Patients Undergoing Advanced Gastrointestinal (GI) Endoscopic Procedures With Propofol

Goudra B., Singh P., Augustus S. American Society of Anesthesiologists 2014; A1230.

A Randomized Controlled Trial of Probability Ramp Control of Propofol for Esophagogastroduodenoscopy

Mandel J.E., Sarraf E. 2014 STA Annual Meeting, January 15-18, Orlando, FL.

Depth of Sedation Does Not Predict Episodes of Apnea

Drover D.R., Tanaka P. Annual Meeting of the International Anesthesia Research Society. San Diego, CA. May 4-7.

Incidence of Deep Sedation and Respiratory Compromise During Procedural Sedation

Applegate R., Macknet M., Qoshlli S., Mehdizadeh A., Jacobson P., Neumann M., Allard M. 2013 Annual Meeting of the International Anesthesia Research Society. San Diego, CA. May 4-7.

Sleep Disruption in the Intensive Care Unit.

Vacas S., McInrue E., Maze M., Leung J. Proceedings of the American Society of Anesthesiologists, October 13, 2012. Washington DC: A396

Sedation in Adults Receiving Mechanical Ventilation: Physiological and Comfort Outcomes.

Grap M.J., Munro C.L., Wetzel P.A., Best A.M., Ketchum J.M., Hamilton V.A., Arief N.Y., Pickler R., Sessler C.N. Am J Crit Care. 2012 May;21(3):e53-e64.

Evaluation of the Sedline to Improve the Safety and Efficiency of Conscious Sedation.

Caputo T.D., Ramsay M.A., Rossmann J.A., Beach M.M., Griffiths G.R., Meyrat B., Barnes J.B., Kerns D.G., Crump B., Bookatz B., Ezzo P. Proc (Bayl Univ Med Cent). 2011 Jul;24(3):200-4.

Incidence of Postoperative Cognitive Dysfunction Following Desflurane or Sevoflurane General Anesthesia in Elderly Patients: a Randomized Controlled Trial.

Nguyen M., Kim A., Applegate R., Rasmussen T., Anderson D., Azer S., Allard M. Proceedings of the 2011 Annual Meeting of the American Society of Anesthesiologists. A614.

Prospective Comparison of Global Electroencephalogram to Frontal Sedline Electroencephalogram Monitoring for the Evaluation of Intraoperative Burst Suppression During Elective Intracranial Surgery.

Nasseri-Noori K.A., McIvor D., Hsu F., Olson M., Allard M., Losey T., Macknet M., Applegate R. Proceedings of the 2011 Annual Meeting of the American Society of Anesthesiologists. A499.

Titration of Sevoflurane in Elderly Patients: Blinded, Randomized Clinical Trial, in Non-Cardiac Surgery after Beta-Adrenergic Blockade.

Drover D.R., Schmiesing C., Buchin A.F., Ortega H.R., Tanner J.W., Atkins J.H., Macario A. J Clin Monit Comput.2011 Jun;25(3):175-81.

Surges of Electroencephalogram Activity at The Time Of Death: A Case Series.

Chawla L.S., Akst S., Junker C., Jacobs B., Seneff M.G. J Palliat Med. 2009 Dec;12(12):1095-100.

Processed Quantitative EEG Monitoring Reduces Postoperative Nausea and Vomiting in Nonsmoking Patients Undergoing Laparoscopic Tubal Ligation.

Cassingham S.F., Khan M., Alaniz P., Munsterman L., Smith C., Kaji S. Proceeding of the 2006 Annual Meeting of the International Anesthesia Research Society: S-163.

Facilitating Perioperative Beta Blockade: Titration of Anesthetic to Processed Electroencephalogram Parameters.

Thong A.E., Gaupp A., Ellis J.E. Proceeding of the 2006 Annual Meeting of the International Anesthesia Research Society: S-65.

Patient State Index.

Drover D., Ortega H.R. Best Pract Res Clin Anaesthesiol. 2006 Mar;20(1):121-8.

Comparison of Depth of Sedation Measured by PSA 4000 and Richmond Agitation-Sedation Scale (RASS).

Sessler C.N., Kollef M., Hamilton A., Grap M.J., Jefferson D. CHEST 2005; 128.

Patient State Index During A Cardiac Arrest In The Operating Room.

Nguyen N.K., Lenkovsky F., Joshi G.P. Anesth Analg. 2005 Jan;100(1):155-7.

Is The Patient State Analyzer With The Psarray2 A Cost-Effective Alternative To The Bispectral Index Monitor During The Perioperative Period?

White P.F., Tang J., Ma H., Wender R.H., Sloninsky A., Kariger R. Anesth Analg. 2004 Nov;99(5):1429-35.

Sedation after Spinal Anesthesia in Elderly Patients: A Preliminary Observational Study with the PSA-4000.

Kurup V., Ramani R., Atanassoff P.G. Can J Anaesth. 2004 Jun-Jul;51(6):562-5.

Assessment of Patient State Index (PSI) and Bispectral Index (BIS) Values during the Recovery Period after Outpatient Surgery.

Tang J., White P. F., Wender R. H. Proceeding of the 2004 Annual Meeting of the International Anesthesia Research Society: S-125.

Comparative Evaluation of Electroencephalographic Patient State Index (PSI) and Bispectral Index (BSI) Values during Ambulatory Anesthesia.

Tang J., White P. F., Wender R. H. Proceeding of the 2004 Annual Meeting of the International Anesthesia Research Society: S-9.

Comparison of Patient State Index (PSI) and Bispectral Index (BSI) Response to Propofol and Desflurane during Ambulatory Surgery.

Tang J., White P. F., Wender R. H. Proceeding of the 2004 Annual Meeting of the International Anesthesia Research Society: S-124.

The Patient State Index as an Indicator of the Level of Hypnosis under General Anaesthesia.

Prichep L.S., Gugino L.D., John E.R., Chabot R.J., Howard B., Merkin H., Tom M.L., Wolter S., Rausch L., Kox W.J. Br J Anaesth. 2004 Mar;92(3):393-9.

Patient State Index (PSI) Measures Depth of Sedation in Intensive Care Patients.

Schneider G., Heglmeier S., Schneider J., Tempel G., Kochs E.F. Intensive Care Med. 2004 Feb;30(2):213-6.

EEG-Based Indices of Anaesthesia: Correlation between Bispectral Index and Patient State Index?

Schneider G., Mappes A., Neissendorfer T., Schabacker M., Kuppe H., Kochs E. Eur J Anaesthesiol. 2004 Jan;21(1):6-12.

A Comparison of Patient State Index (PSI) Changes and Remifentanil Requirements during Cardiopulmonary Bypass in Infants Undergoing General Anesthesia with or without Spinal Anesthesia.

Drover D., Hammer G.B., Williams G., Boltz M., Ramamoorthy C. Anesthesiology 2004; 101: A1453.

The Response of the Patient State Index (PSI) to Different Anesthetic Types.

Drover D., Plourde G., Loyd G., Ortega H.R., Frazer D. Anesthesiology 2004; 101: A339.

Validation of the EEG Electrode Placement for the Patient State Index (PSI).

Drover D., Plourde G., Loyd G., Ortega H.R., Frazer D. Anesthesiology 2004; 101: A322.

The Patient State Index Correlates Well with the Ramsay Sedation Score in ICU Patients.

Ramsay M.A., Huddleston P., Hamman B., Tai S., Greg M. Anesthesiology 2004; 101: A338.

The Patient State Index Is an Indicator of Inadequate Pain Management in the Unresponsive ICU Patient.

Ramsay M.A., Huddleston P., Henry C., Marcel R., Tai S. Anesthesiology 2004; 101: A349.

Nurse-Administered Propofol Sedation (NAPS) for Gastrointestinal Endoscopic Procedures: NAPS or NAPA?

Ramsay M.A., M Hein T. Anesthesiology 2004; 101: A68.

Is Patient State Index of EEG Better Than Bispectral Index of EEG in Assessing Different Levels of Sedation as Judged by Ramsey Sedation Score in ICU Patients?

Shah N., Quijano A. Anesthesiology 2004; 101: A293.

The Impact of Addition of N2O on BIS, PSI, and Entropy during a Stable Sevoflurane Anesthetic.

Soto R.G., Smith R.A., Miguel R.V. Anesthesiology 2004; 101: A334.

Detection of Awareness in Surgical Patients with EEG-Based Indices - Bispectral Index and Patient State Index.

Schneider G., Gelb A.W., Schmeller B., Tschakert R., Kochs E. Br J Anaesth. 2003 Sep;91(3):329-35.

The Impact of Addition of N2O on BIS and PSI during a Stable Sevoflurane Anesthetic.

Soto R.G., Fu E.S., Creighton D.D. Anesthesiology 2003; 99: A319.

The Physiometrix PSA 4000 Decreases Propofol Usage and Hastens Discharge in Gynecological Day Surgery Procedures.

Cassingham S.F., Hebert T., Lemaire R., Cook R., McPherson P.K. Anesthesiology 2002; 96: A5.

Physiometrix PSA 4000 Processed EEG Monitoring Augments the Anesthesia Sparing Effect of Dexmedetomidine.

Cassingham S.F., Hebert T., Cook R., Biggs R., McPherson P.K. Anesthesiology 2002; 96: A546.

A Comparison Of Patient State Index And Bispectral Index Values During The Perioperative Period.

Chen X., Tang J., White P.F., Wender R.H., Ma H., Sloninsky A., Kariger R. Anesth Analg. 2002 Dec;95(6):1669-74.

Titration of Delivery and Recovery from Propofol, Alfentanil, and Nitrous Oxide Anesthesia.

Drover D.R., Lemmens H.J., Pierce E.T., Plourde G., Loyd G., Ornstein E., Prichep L.S., Chabot R.J., Gugino L. Anesthesiology 2002; 97:82–9.

Can the Patient State Index (PSI) Be Used a Measure of Sedation on the Intensive Care Unit (ICU)?

Schneider G., Heglmeier S., Schneider J., Kochs, E. Anesthesiology 2002; 96: A298.

Detection of Awareness during Anesthesia: Bispectral Index (BIS) or Patient State Index (PSI)?

Schneider G., Grineisen Y., Heindl B.K., Kochs E.F. Anesthesiology 2002; 96: A312.

Comparison of PSA and BIS Monitoring during General Anesthesia with Propofol and Desflurane.

Tang J., Chen X., White P.F., Wender R., Naruse R. Proceeding of the 2002 Annual Meeting of the International Anesthesia Research Society: S-21.

Quantitative EEG Changes Associated With Loss And Return Of Consciousness In Healthy Adult Volunteers Anaesthetized With Propofol Or Sevoflurane.

Gugino L.D., Chabot R.J., Prichep L.S., John E.R., Formanek V., Aglio L.S. Br J Anaesth. 2001 Sep;87(3):421-8.

Invariant Reversible QEEG Effects of Anesthetics.

John E.R., Prichep L.S., Kox W., Valdés-Sosa P., Bosch-Bayard J., Aubert E., Tom M., di Michele F., Gugino L.D. Conscious Cogn. 2001 Jun;10(2):165-83.

QEEG Changes Correlate with Quality of Emergence from General Anesthesia.

Gugino L., Chabot R., Aglio L., Block-Salisbury E., Prichep L., John E.R. Anesthesiology 2001; 95:A288.

Patient State Index Assesses Arousal Level.

Gugino, L., Chabot, R., Aglio, L., Prichep, L., Formanek, V. Anesthesiology 2001; 95:A282.

Comparison of Bispectral Index and Patient State Index during Induction of Anesthesia for Open Heart Surgery.

Mappes A., Gruendel A., Kuppe H. Anesthesiology 2001; 95:A279.

Patient State Index (PSI): Optimization of Delivery and Recovery from Propofol, Alfentanil and Nitrous Oxide Anesthesia.

Pierce, E.T., Drover, D., Plourde, G., Loyd, G., Eugene, O. Anesthesiology 2001; 95:A283.

Women Patients Require More Propofol for General Anesthesia than Men.

Prichep L. Drover D., Anesthesiology 2001; 95:A481.

Clinical Evidence Key:

Indicates a PDF document

Indicates an abstract or presentation / indicates peer-reviewed journal article

Indicates peer-reviewed journal article

Duplicate abstracts or publications are excluded

This section is intended to provide access to clinical studies conducted using Masimo noninvasive technologies, parameters, and products. We cannot guarantee that all published clinical studies, abstracts and research are listed here. To view individual clinical studies please click on the appropriate tab.

Some uses of the manufacturer’s devices described in the information may not have been approved or cleared by the FDA. See manufacturer labeling for the indications in the product’s cleared indications for use statement.

Clinical evidence is provided to illustrate the performance and accuracy of Masimo technologies. Federal law restricts Masimo devices for medical uses to sale by or on the order of a physician.