SpMet is a breakthrough measurement that allows clinicians to noninvasively and continuously monitor levels of methemoglobin in the blood—a form of hemoglobin that is incapable of carrying oxygen
- > The administration of many drugs commonly used in hospitals–such as lidocaine, benzocaine, dapsone, and nitrates–may result in acquired methemoglobinemia which impairs oxygen delivery to tissues.1
- > While methemoglobinemia can occur in all care areas and patients, it is often unrecognized and misdiagnosed.1,2
- > If not identified and treated, it can result in
avoidable injury or death.
Medications Known to Increase Methemoglobin Levels in the Blood:
Benzocaine, Cetacaine, Chloroquine, Dapsone, EMLA topical, Flutamide, Lidocaine, Metoclopramide, Nitrates, Nitric oxide, Nitroglycerin, Nitroprusside, Nitrous oxide, Phenazopyridine (Pyridium), Prilocaine, Primaquine, Riluzole, Silver nitrate, Sodium nitrate, Sulfonamides.
Prevalence of Methemoglobinemia
|Patient Age||Care Areas||Fatalities|
(2.5 cases per hospital per month)
|4 days to 86 years||Surgery, intensive care, outpatient clinics, pediatrics,
emergency department, cardiac cath lab
3 near fatalities
"Acquired methemoglobinemia is fairly common and causes morbidity and mortality in both the inpatient and outpatient settings. Acquired methemoglobinemia is often unrecognized and thus untreated."
Dr. Rachel Ash-Bernal
and other researchers at Johns Hopkins Hospital
- 1 Ash-Bernal RA et al. Medicine. 2004;83:265-273.
Upgradable rainbow SET® Technology Platform
Masimo rainbow SET® is a noninvasive monitoring platform featuring Masimo SET®
Measure-through Motion and Low Perfusion™ pulse oximetry with the option to
measure multiple additional blood constituents and physiologic parameters.
- > Oxygen Saturation (SpO2)
- > Pulse Rate (PR)
- > Perfusion Index (PI)
- > Total Hemoglobin
- > Oxygen Content (SpOC™)
- > Pleth Variability Index (PVI®)
- > Methemoglobin (SpMet®)
- > Carboxyhemoglobin (SpCO®)
- > Acoustic Respiration Rate (RRa®)
The upgradeable rainbow® platform lets you choose the rainbow® measurements that are right for you now and be confident that your investment in patient safety won’t become obsolete tomorrow.
SpMet monitoring with Radical-7 is not intended to replace laboratory blood testing. Blood samples should be analyzed by laboratory instruments prior to clinical decision making.
Caution: Federal (USA) law restricts this device to sale by or on the order of a physician. See instructions for use for full prescribing information, including indications, contraindications, warnings, and precautions.