Phasein Technology

The Ultimate in Capnography and Gas Monitoring Performance

In 2012, Masimo acquired Phasein, a leading developer of capnography and gas monitoring technologies.  Masimo is commercializing Phasein technology through its OEM and worldwide distribution channels, as well as initiating next-generation capnography and gas monitoring technology and product development.

Phasein technology advantages

  • > Unique sidestream and mainstream options
  • Allows selection of the modality best suited to the application
  • > Capnography and gas monitoring measurements
  • Largest reach to access all markets
  • > Smallest, lowest power technology boards
  • Facilitates easy integration
  • > Internal or external integration
  • Flexible and adaptable for both OEMs and customers
  • > Immediate and continuous monitoring
  • No warm up required or calibration delays during monitoring
  • > Nomoline disposable for multi-patient use
  • Significantly decreases consumable costs

Advanced technical features and benefits

Phasein spectrometer
Phasein’s sophisticated spectrometer detects the slightest changes in infrared radiation at nine different wavelengths in the LWIR spectrum to precisely determine gas concentrations in a mixture. The Phasein spectrometer has a true single beam design, eliminating frequent zeroing, which is common to older designs using dual beam sensors or beam splitters.

Phasein can be tailored to a variety of applications ranging from single gas capnography to state-of-the-art multigas measurements of carbon dioxide (CO2), nitrous oxide (N2O), and binary anesthetic agents, with agent identification. In addition to the ISA, OR+ analyzer has an O2 option that utilizes a long-life paramagnetic oxygen sensor. Irrespective of the application, the Phasein spectrometer deliveries state-of-the-art performance in a package weighing less than 5g.

No cross interference or broadening effects
The Phasein spectrometer uses the 4 to 10 μm LWIR wavelength band to precisely measure the infrared absorption caused by molecules in the gas sample. The LWIR wavelength band contains strong absorption peaks for CO2, N2O, and the anesthetic agents, with negligible interference from alcohol, acetone, and other gases and vapors that could potentially degrade measurement accuracy. In the multigas versions, seven carefully selected narrow band optical filters are used to trace the gas sample composition, while two filters are used for temperature compensation to provide accurate measurements under a variety of conditions. The precisely tuned optical filter set provides for high signal-­to-­noise ratio gas measurements, as well as automatic compensation for cross interference; broadening effects caused by oxygen, nitrous oxide, and anesthetic agents; and pressure broadening effects.

Crisp waveforms in any clinical situation
Every detail in a Phasein sidestream analyzer has been engineered to precisely depict the clinical situation, even for young patients with very high breathing rates. To be able to measure under such extreme conditions, the measuring chamber of the Phasein spectrometer has been compressed to 50 μl (micro liters). Phasein technology delivers the world’s first multigas sidestream analyzer with a 50 mL/min sampling flow specifically designed for all patients, from adults to neonates.

Patented gas measurement algorithms
In the Phasein spectrometer, the flow controller and the micro-­pump are controlled by a 32-­bit RISC microprocessor. Analog pressure, temperature, and flow signals combined with data from the Phasein spectrometer are processed using complex, matrix calculations. The latest advances in digital signal processing provide unparalleled gas measurement accuracy and reliable agent gas identification in any clinical situation.

Temperature stabilized gas analysis
The sidestream analyzers are designed without the need for heaters or coolers. Instead, three temperature sensors and two optical filters in the Phasein spectrometer are used to compensate for temperature variations and gradients. The result is not only an impressive low-power consumption, but also "instant on” performance. Accurate data is available within 10 seconds, and full accuracy for anesthetic agentsis available within one minute from power on.

High efficiency LWIR light source
Phasein technology features its own infrared source to provide excellent power efficiency and stability. A specially designed parabolic reflector focuses the infrared beam so that no energy is lost. This means the sidestream analyzers can deliver high fidelity gas data while maintaining micro power operation.

Light emitting gas inlet – LEGI™
The advanced LEGI gas inlet detects the presence of the Nomoline sampling line and a status indicator conveys color-­coded information about the bench status and the alarm system. LEGI interfaces directly to Nomoline for optimal performance and protection from water, mucus, and bacterial contamination. When no sampling line is connected, the sidestream analyzer automatically enters into a low-power, standby mode. Once the sampling line is connected, the ISA sidestream analyzer enters into measurement mode and begins delivering gas data immediately.

Nomoline - No moisture, no water traps
Phasein ISA sidestream analyzers interface to the Nomoline family of gas sampling lines; the world’s first sampling lines that remove both water and water vapor from the sample flow.

Integrated flow controller
Phasein ISA sidestream analyzers, despite their compact design, integrate an advanced flow controller that secures a stable low flow of 50 mL/min for all applications, and under varying ambient conditions. Unlike other less sophisticated solutions, Phasein sidestream analyzers automatically handle both patient and exhaust pressure variations, as well as a wide ambient temperature and pressure range. A gas reference valve is also provided to facilitate automatic span calibration of the optional oxygen sensor.

Durable micro pump
The integrated, high-reliability micro pump is fitted with a low-power, brushless motor. Three miniature ball bearings ensure trouble-free operation without the need for regular maintenance. The balanced shaft design and integrated pneumatic filter virtually eliminate pressure and flow variations.

Universal interface protocol
Phasein ISA sidestream technology utilizes a proprietary interface protocol, common to all our products, ranging from the IRMA mainstream CO2 sensors to ISA sidestream multigas analyzers. Changing from a mainstream to a sidestream option is as simple as “plug-in and measure."

Rugged design
The ISA analyzers are lightweight, have a rugged design, and are engineered for a wide range of clinical application, including emergency and transport applications.

Factory calibrated
Phasein ISA sidestream analyzers are factory calibrated and do not require calibration in the field.

PDF Resources

Which One?
Anesthesia Gas Monitoring:
Evolution of a de facto Standard of Care
Trouble-free sidestream gas analysis
Mainstream Gas Analyzers:
A Historical and Technological Perspective