SpHb®Total Haemoglobin

Continuous SpHb provides real-time visibility to changes, or lack of changes, in haemoglobin between invasive blood samples

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Limitations of Traditional Methods Alone

Without SpHb, clinicians are often limited to invasive blood samples, which provide intermittent and delayed laboratory haemoglobin results



Value of SpHb Monitoring

SpHb can be used in conjunction with traditional laboratory methods to obtain real-time visibility to changes, or lack of changes, in haemoglobin between invasive blood samples

value of sphb

SpHb trend monitoring may provide additional insight between invasive blood samples when:

  • > The SpHb trend is stable and the clinician may otherwise think haemoglobin is dropping
  • > The SpHb trend is rising and the clinician may otherwise think haemoglobin is not rising fast enough
  • > The SpHb trend is dropping and the clinician may otherwise think haemoglobin is stable

Clinical Case

SpHb was retrospectively obtained for the surgical case shown below, in which clinicians could not assess the haemoglobin trend between invasive blood samples during the procedure1

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SpHb Utility

Studies have shown that SpHb may help clinicians reduce blood transfusions in both low and high blood loss surgeries2,3

  • > A randomised trial of 327 patients undergoing elective orthopaedic surgery, conducted at Massachusetts General Hospital (MGH), found that the use of continuous, noninvasive haemoglobin monitoring reduced the rate of transfusions when compared to standard care without continuous, noninvasive haemoglobin monitoring2
graph 1
  • > A prospective cohort study of 106 neurosurgical patients found that adding SpHb monitoring to standard-of-care blood management resulted in decreased blood utilisation in high-blood-loss neurosurgery, while also facilitating earlier transfusions3*
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Clinical decisions regarding red blood cell transfusions should be based on the clinician’s judgment considering among other factors: patient condition, continuous SpHb monitoring, and laboratory diagnostic tests using blood samples.

* Study Protocol:The transfusion threshold of 10g/dL was predetermined by the study protocol and may not be appropriate for all patients. The blood sampling technique was the same for patients in both the control and the test group. Arterial blood was drawn from a 20 gauge radial artery cannula into 2mL ethylenediaminetetraacetic acid collection tubes, thoroughly mixed then sent immediately to the central lab for analysis by a haematology analyser. The reference laboratory device used for haemoglobin measurements in the study was a Coulter GEN-S Hematology Analyzer.


SpHb Monitoring Across the Continuum of Care

Monitoring haemoglobin continuously and noninvasively through different care areas



Upgradable rainbow SET Technology Platform

Masimo rainbow SET is a noninvasive monitoring platform featuring Masimo SET® Measure-through Motion and Low Perfusion pulse oximetry with the option to measure multiple additional parameters

  • > Oxygen Saturation (SpO2)
  • > Pulse Rate (PR)
  • > Perfusion Index (Pi)
  • > Pleth Variability Index (PVi®)
  • > Oxygen Content (SpOC)
  • > Oxygen Reserve Index (ORi)
  • > Total Haemoglobin (SpHb)
  • > Methaemoglobin (SpMet®)
  • > Carboxyhaemoglobin (SpCO®)
  • > Acoustic Respiration Rate (RRa®)
  • > Respiration Rate from the Pleth (RRp)

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  • 1 Peiris P. et al. Proceeding for the Society for the Advancement of Blood Medicine 2010 Annual Meeting. Abs 4091.
  • 2 Ehrenfeld et al. J Blood Disorders Transf. 2014. 5:9.
  • 3 Awada WN et al. J Clin Monit Comput. DOI 10.1007/s10877-015-9660-4.


  • > Click here for available SpHb studies.
  • > Click here to receive more information about noninvasive and continuous SpHb.
Brochure SpHb Brochure
Noninvasive and Continuous haemoglobin (SpHb) Monitoring
Whitepaper SpHb Whitepaper
Noninvasive and Continuous Haemoglobin
Brochure Perioperative Care Solutions Brochure
Perioperative Care Solutions

SpHb monitoring is not intended to replace laboratory blood testing. Blood samples should be analysed by laboratory instruments prior to clinical decision making.

For professional use. See instructions for use for full prescribing information, including indications, contraindications, warnings, and precautions.

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