Clinical Evidence - Pleth Variability Index (PVI^®)

PVI provides an indicator of the variability of the perfusion index (PI).

Featured Clinical Studies:

Goal-Directed Fluid Management Based on the Pulse Oximeter-Derived Pleth Variability Index Reduces Lactate Levels and Improves Fluid Management. Forget P, Lois F, de Kock M. Anesth Analg. 2010 Oct;111(4):910-4.
Pleth Variability Index Predicts Fluid Responsiveness in Critically Ill Patients. Loupec T., Nanadoumgar H., Frasca D., Petitpas F., Laksiri L., Baudouin D., Debaene B., Dahyot-Fizelier C., Mimoz O. Crit Care Med. 2011 Feb;39(2):294-9.
Accuracy of Stroke Volume Variation Compared with Pleth Variability Index to Predict Fluid Responsiveness in Mechanically Ventilated Patients Undergoing Major Surgery. Zimmermann M., Feibicke T., Keyl C., Prasser C., Moritz S., Graf B.M., Wiesenack C. Eur J Anaesthesiol. 2010 Jun;27(6):555-61.
Pleth Variability Index to Monitor the Respiratory Variations in the Pulse Oximeter Plethysmographic Waveform Amplitude and Predict Fluid Responsiveness in the Operating Theatre. Cannesson M., Desebbe O., Rosamel P., Delannoy B., Robin J., Bastien O., Lehot J.J. Br J Anaesth. 2008 Aug;101(2):200-6.

Full Citation List of All Available Studies:*

External Pressure Applied on the Caval Vein and its Effects on Difference in Pulse Pressure (Dpp) and Pleth Variability Index (PVI). Strys L.T., Closhen D., Fukui K., Günter H., Wilke W., Pestel G. EJA 2012; 29: May 2012 Supplement. Abs 643.
Plethysmographic Variability Index does not Predict Fluid Responsiveness in Cardiac Surgery Patients. Fischer M.O., Rebet O., Lecrivain V., Gérard J.L., Hanouz J.L., Fellahi J.L. EJA 2012; 29: May 2012 Supplement. Abs 799.
The Increase of Vasomotor Tone Avoids the Ability to Predict Fluid Responsiveness of the Dynamic Preload Indicators Bouchacourt J.P., Grignola J.C., Riva1 J. BJA 2012; 108 (S2): paper no. 1098.0
Low Tidal Volume Does Not Affect the Dynamic Indicators of Fluid Responsiveness Bouchacourt J.P. BJA 108 (S2): paper no. 1094.0
Use of PVI for Guidance of Fluid Management during Major Abdominal Surgery Lahner D., Kabon B., Muhlbacher J., Fleischmann E., Hetz H. BJA 108 (S2): paper no. 480.00
First Day of Life Reference Values for Pleth Variability Index in Spontaneously Breathing Term Newborns. Latini G., Dipaola L., De Felice C. Neonatology. 2012;101(3):179-182.
Stroke Volume Variation and Pleth Variability Index to Predict Fluid Responsiveness during Resection of Primary Retroperitoneal Tumors in Hans Chinese Fu Q., Mi W.D., Zhang H. Biosci Trends. 2012 Feb;6(1):38-43.
Pulse Oximeter Plethysmograph Variation and its Relationship to the Arterial Waveform in Mechanically Ventilated Children Chandler J.R., Cooke E., Petersen C., Karlen W., Froese N., Lim J., Ansermino J.M. J Clin Monit Comput. 2012 Mar 10.
Dynamic variables of fluid responsiveness during pneumoperitoneum and laparoscopic surgery. Høiseth L.O., Hoff I.E., Myre K., Landsverk S.A., Kirkebøen K.A. Acta Anaesthesiol Scand. 2012 Jan 31.
The Effects of Epidural Anesthesia on Difference in Pulse Pressure (dPP) and Pleth Variability Index (PVI). Fukui K., Latz B., Markstaller K., Ikeda M., Pestel G. Proceedings of the 2011 Annual Meeting of the American Society of Anesthesiologists. A867.
Relationship between Differential Distribution of Blood Flow to Blocked or Unblocked Areas and the Extent of the Sensory Block in Spinal Anesthesia. Imai E., Tanaka S., Kawamata T., Kawamata M. Proceedings of the 2011 Annual Meeting of the American Society of Anesthesiologists. A667.
Can the Starting Pulse Oximeter-Derived Pleth Variability index (PVI) Predict Total Crystalloid Replacement during Isovolemic Hemodilution in Congenital Cardiac Surgery? Naguib A.N., Winch P., Rice J., Tobias J. Proceedings of the 2011 Annual Meeting of the American Society of Anesthesiologists. A207.
Changes in Stroke Volume Variation (SVV) and Pleth Variability Index (PVI) During Rapid Colloid Infusion. Shimizu F., Hishinuma N., Shimizu S., Tanaka S., Kawamata M. Proceedings of the 2011 Annual Meeting of the American Society of Anesthesiologists. A869.
The Effectiveness of Pleth Variability Index to Predict Hypotension Induced by Spinal Anesthesia for Cesarean Delivery. Yoshioka M., Yamada, T., Miyake W., Tanaka K., Nishikawa K. Proceedings of the 2011 Annual Meeting of the American Society of Anesthesiologists. A960.
Pleth Variability Index to Predict Fluid Responsiveness in Colorectal Surgery. Hood J.A., Jonathan R., Wilson T. Anesth. Analg. 2011;113:1058–63.
Impact of Skin Incision on the Pleth Variability Index. Takeyama M, Matsunaga A, Kakihana Y, Masuda M, Kuniyoshi T, Kanmura Y. J Clin Monit Comput 2011 Aug;25(4):215-21.
Impact of Norepinephrine on the Relationship between Pleth Variability Index and Pulse Pressure Variations in ICU Adult Patients. Biais M. , Cottenceau V., Petit L. , Masson F. , Cochard J.F., Sztark F. Critical Care 2011, 15:R168.
Non-invasive Prediction of Fluid Responsiveness in Infants Using Pleth Variability Index. Renner J., Broch O., Gruenewald M., Scheewe J., Francksen H., Jung O., Steinfath M., Bein B. Anaesthesia. 2011 Jul;66(7):582-9.
Accuracy of the Pleth Variability Index to Predict Fluid Responsiveness Depends on the Perfusion Index. Broch O., Bein B., Gruenewald M., Höcker J., Schöttler J., Meybohm P., Steinfath M., Renner J. Acta Anaesthesiol Scand. 2011 Jul;55(6):686-93.
Influence of the Site of Measurement on the Ability of Plethysmographic Variability Index to Predict Fluid Responsiveness. Desgranges F.P., Desebbe O., Ghazouani A., Gilbert K., Keller G., Chiari P., Robin J., Bastien O., Lehot J.J., Cannesson M. Br. J. Anaesth. 2011 Jun 16.
Predicting Fluid Responsiveness in Mechanically Ventilated Children under General Anaesthesia using Dynamic Parameters and Transthoracic Echocardiography. Pereira de Souza Neto E., Grousson S., Duflo F., Ducreux C., Joly H., Convert J., Mottolese C., Dailler F., Cannesson M. Br J Anaesth. 2011 Jun;106(6):856-64.
Volume Responsiveness in Children, A Comparision of Static and Dynamic Indices. Chandler J., Cooke E., Hosking M., Froesel N., Karlen W., Ansermino J. IARS 2011 Annual Meeting. S-200.
Plethysmography Variability Index: Comparison with Pulse Pressure Variation in Vascular Surgery. Guinet P., Daviet L., Wodey E., Laviolle B., Ecoffey C. Eur J Anaesthesiol. 2011; May:1284.
Difference Between Pleth Variability Index Obtained from the Finger and the Forehead. Matsunaga A., Kakihana Y., Kuniyoshi T., Kumemura M., Uchida Y., Kanmura Y. Eur J Anaesthesiol. 2011; May:1186.
What is the Best Site for Measuring the Pleth Variability Index (PVI) during a Surgery Procedure? Pavlakovitch I., Desebbe O., Cannesson M., Bastien O., Lehot J.J. Eur J Anaesthesiol. 2011; May:Abs 1306.
Pleth Variability Index Predicts Fluid Responsiveness in Critically Ill Patients. Loupec T., Nanadoumgar H., Frasca D., Petitpas F., Laksiri L., Baudouin D., Debaene B., Dahyot-Fizelier C., Mimoz O. Crit Care Med. 2011 Feb;39(2):294-9.
Goal-Directed Fluid Management Based on the Pulse Oximeter-Derived Pleth Variability Index Reduces Lactate Levels and Improves Fluid Management. Forget P, Lois F, de Kock M. Anesth Analg. 2010 Oct;111(4):910-4.
Pulse Oximetry Plethysmographic Waveform Changes during Cesarean Section under Spinal Anesthesia. Chassard D., Chandesris V., Rhondali O. Proceedings of the 2010 Annual Meeting of the American Society of Anesthesiologists. A1287.
Stroke Volume, Pulse Pressure, PVI and PI during Spontaneous Ventilation in a Model of Hypovolemia. Hoiseth L.O., Hoff I.E., Hisdal J., Landsverk S., Kirkeboen K.A. Proceedings of the 2010 Annual Meeting of the American Society of Anesthesiologists. A576.
Accuracy of Stroke Volume Variation Compared with Pleth Variability Index to Predict Fluid Responsiveness in Mechanically Ventilated Patients Undergoing Major Surgery. Zimmermann M., Feibicke T., Keyl C., Prasser C., Moritz S., Graf B.M., Wiesenack C. Eur J Anaesthesiol. 2010 Jun;27(6):555-61.
Pleth Variability Index Predicts Hypotension During Anesthesia Induction. Tsuchiya M., Yamada T., Asada A. Acta Anesthesiol Scand. 2010 May;54(5):596-602.
Are Respiratory Induced Changes in Pulse Pressure and Pulse Oximeter Plethysmography Wave Amplitude Related in Ventilated Children? Chandler J.R., Cooke E., Petersen C., Froese N., Lim J., Ansermino J. Anesth Analg. 2010; 110 (3):S-257.
The Ability of Pleth Variability Index to Predict the Hemodynamic Effects of Positive End-Expiratory Pressure in Mechanically Ventilated Patients Under General Anesthesia. Desebbe O., Boucau C., Farhat F., Bastien O., Lehot J.J., Cannesson M. Anesth Analg. 2010 Mar 1;110(3):792-8.
Pleth Variability Index Combined with Passive Leg Raising-Induced Pulse Pressure Variation to Detect Hypovolemia in Spontaneously Breathing Patients. Schoonjans A., Forget P., Labriola L., Deneys V., Jadoul M., Pingaut I., De Kock M. Acta Anaesthesiol Belg. 2010;61(3):147-50.
The Change of Upper Limbs PVI in Spinal Block (The Comparison in High Spinal Block and Non-High Spinal Block). Takeyama K., Yoshikawa M. Eur J Anaesthesiol. 2009; 26 (Suppl 45): 3AP5-1.
Plethysmography Variability Index: A New Fluid Responsiveness Parameter. Feissel M., Kalakhy R., Badie J., Robles G, Faller J., Teboul J.L. Critical Care 2009, 13(Suppl 1).
Effect of Preload Changes on Pleth Variability Index during Liver Transplants. Lobo E., Niemann C., Talke P. Anesth Analg 2009; 108:S-171.
Impact of Lower Extremity Nerve Blockade on Oximeter Perfusion Index & Pleth Variability Index. Allred D.V., Shah N.K., Estanol L. Anesthesiology 2008; 109: A1603.
Ability of Pleth Variability Index to Detect Preload Changes in Orthotopic Liver Transplant Patients. Wray C., Buckley J., Kwan D., Maktabi T., Mahajan A. Anesthesiology 2008; 109 A1605.
Pleth Variability Index to Monitor the Respiratory Variations in the Pulse Oximeter Plethysmographic Waveform Amplitude and Predict Fluid Responsiveness in the Operating Theatre. Cannesson M., Desebbe O., Rosamel P., Delannoy B., Robin J., Bastien O., Lehot J.J. Br J Anaesth. 2008 Aug;101(2):200-6.
Does the Pleth Variability Index Indicate the Respiratory-Induced Variation in the Plethysmogram and Arterial Pressure Waveforms? Cannesson M., Delannoy B., Morand A., Rosamel P., Attof Y., Bastien O., Lehot J.J. Anesth Analg. 2008 Apr;106(4):1189-94.
Ability of Pleth Variability Index to Detect Hemodynamic Changes Induced by Passive Leg Raising in Spontaneously Breathing Volunteers Keller G., Cassar E., Desebbe O., Lehot J.J., Cannesson M. Crit Care. 2008;12(2):R37.
Use of Pleth Variability Index (PVI) to Detect Changes in Intrathoracic Pressure. Goldstein M., Lopez M., Saesim D., Peverini R. Proceedings of the 2007 Annual Meeting of the American Association for Respiratory Care. A1287.

* Abstracts of studies subsequently published in scientific journals and duplicate abstracts or publications are excluded.

indicates an abstract or presentation.

indicates peer-reviewed journal article.